Sepia is a homeopathic remedy often given to women suffering with sadness, indifference, anger, hot flashes and in some cases constipation. Other indications for its use include a strong craving for the heat of the sun, heat and perspiration at menopause. Can be worse standing, mental labor, sexual excess and menopause. Tends to be better in the open air, sitting with legs crossed and with loose clothing. This homeopathic remedy is made from a saltwater organism called the common cuttlefish.